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A Kinetic Model of Single and Clustered IP(3) Receptors in the Absence of Ca(2+) Feedback

Ca(2+) liberation through inositol 1,4,5-trisphosphate receptor (IP(3)R) channels generates complex patterns of spatiotemporal cellular Ca(2+) signals owing to the biphasic modulation of channel gating by Ca(2+) itself. These processes have been extensively studied in Xenopus oocytes, where imaging...

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Detalhes bibliográficos
Main Authors: Shuai, Jianwei, Pearson, John E., Foskett, J. Kevin, Mak, Don-On Daniel, Parker, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929031/
https://ncbi.nlm.nih.gov/pubmed/17526578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.108795
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