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Single-Channel Kinetics, Inactivation, and Spatial Distribution of Inositol Trisphosphate (IP(3)) Receptors in Xenopus Oocyte Nucleus

Single-channel properties of the Xenopus inositol trisphosphate receptor (IP(3)R) ion channel were examined by patch clamp electrophysiology of the outer nuclear membrane of isolated oocyte nuclei. With 140 mM K(+) as the charge carrier (cytoplasmic [IP(3)] = 10 μM, free [Ca(2+)] = 200 nM), the IP(3...

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Detalhes bibliográficos
Main Authors: Mak, Don-On Daniel, Foskett, J. Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217068/
https://ncbi.nlm.nih.gov/pubmed/9154905
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