Conversion of inactive glycosylation inhibiting factor to bioactive derivatives by modification of a SH group

Escherichia coli-derived recombinant human glycosylation inhibiting factor (rhGIF) contains three cysteine residues (Cys-57, -60, and -81). All SH groups in the cysteine residues are free, and the GIF molecule had no biologic activity. Carboxymethylation of the SH group of Cys-60 in the molecule res...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Nakano, Tatsumi, Watarai, Hiroshi, Liu, Yun-Cai, Oyama, Yukihito, Mikayama, Toshifumi, Ishizaka, Kimishige
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1997
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19284/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8990186/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.1.202
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