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Conversion of inactive glycosylation inhibiting factor to bioactive derivatives by modification of a SH group

Escherichia coli-derived recombinant human glycosylation inhibiting factor (rhGIF) contains three cysteine residues (Cys-57, -60, and -81). All SH groups in the cysteine residues are free, and the GIF molecule had no biologic activity. Carboxymethylation of the SH group of Cys-60 in the molecule res...

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Autors principals: Nakano, Tatsumi, Watarai, Hiroshi, Liu, Yun-Cai, Oyama, Yukihito, Mikayama, Toshifumi, Ishizaka, Kimishige
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19284/
https://ncbi.nlm.nih.gov/pubmed/8990186
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