Increased renal uptake of gentamicin in endotoxemic rats receiving concomitant thromboxane A2 antagonist therapy.

This report describes the effects of endotoxin and a thromboxane receptor antagonist, L-655,240, on kidney function and the intrarenal pharmacokinetics of aminoglycosides. The rationale for these studies was that thromboxane antagonists may eventually be used in combination with aminoglycosides in p...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Tardif, M, Bergeron, Y, Beauchamp, D, Bergeron, M G
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8109943/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.12.2727
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