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Influence of endotoxin on the intracortical accumulation kinetics of gentamicin in rats.

The mechanism by which endotoxin (lipopolysaccharide [LPS]) modifies the intrarenal distribution and the nephrotoxic potential of gentamicin is unknown. We studied the influence of LPS on the intracortical accumulation kinetics of gentamicin in rats infused intravenously for 6 h, during which time s...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Tardif, D, Beauchamp, D, Bergeron, M G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171646/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2344164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.4.576
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