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Prolonged endotoxemia enhances the renal injuries induced by gentamicin in rats.

The aim of this study was to evaluate the role of chronic endotoxemia in the nephrotoxicity of gentamicin (GM). Saline or Escherichia coli lipopolysaccharide (LPS) was administered to conscious rats by continuous intravenous perfusion (1 mg/kg per day for 7 days) from a subcutaneously implanted osmo...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Auclair, P, Tardif, D, Beauchamp, D, Gourde, P, Bergeron, M G
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171712/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2360824/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.5.889
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