Correlation of tobramycin-induced inhibition of protein synthesis with postantibiotic effect in Escherichia coli.

Scant data exist on intracellular events during aminoglycoside-induced postantibiotic effect (PAE). We examined DNA, RNA, and protein syntheses after tobramycin exposure using [3H]thymidine, [14C]uracil, and [14C]alanine incorporation in a clinical Escherichia coli strain. Late-log-phase bacteria in...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Barmada, S, Kohlhepp, S, Leggett, J, Dworkin, R, Gilbert, D
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1993
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192776/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.12.2678
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