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Correlation of tobramycin-induced inhibition of protein synthesis with postantibiotic effect in Escherichia coli.

Scant data exist on intracellular events during aminoglycoside-induced postantibiotic effect (PAE). We examined DNA, RNA, and protein syntheses after tobramycin exposure using [3H]thymidine, [14C]uracil, and [14C]alanine incorporation in a clinical Escherichia coli strain. Late-log-phase bacteria in...

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Bibliografiske detaljer
Main Authors: Barmada, S, Kohlhepp, S, Leggett, J, Dworkin, R, Gilbert, D
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC192776/
https://ncbi.nlm.nih.gov/pubmed/7509145
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