Evolutionary matches of enzyme and transporter capacities to dietary substrate loads in the intestinal brush border

Safety factors of enzymes and transporters are defined as the ratio of V(max) (maximal reaction rates at high substrate concentrations) to the reaction rate under actual physiological conditions. Although corresponding safety factors have been measured for macroscopic biological structures and for h...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Weiss, Stacey L., Lee, Eric A., Diamond, Jared
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1998
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19269/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9482848/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.5.2117
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