Interaction between the α-glucosidases, sucrase-isomaltase and maltase-glucoamylase, in human intestinal brush border membranes and its potential impact on disaccharide digestion

The two major intestinal α-glycosidases, sucrase-isomaltase (SI) and maltase-glucoamylase (MGAM), are active towards α-1,4 glycosidic linkages that prevail in starch. These enzymes share striking structural similarities and follow similar biosynthetic pathways. It has been hypothesized that starch d...

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Autores principales:	Stephanie Tannous, Tammy Stellbrinck, Abdullah Hoter, Hassan Y. Naim
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2023-03-01
Colección:	Frontiers in Molecular Biosciences
Materias:	sucrase-isomaltase maltase-glucoamylase human brush border membrane protein-protein interaction digestive function carbohydrates
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fmolb.2023.1160860/full
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