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Two-state models of protein folding kinetics

The folding of some proteins appears to be a two-state kinetic process. A two-state kinetic model is justified if protein molecules rapidly equilibrate between different unfolded conformations prior to complete folding. Here I show that this rapid equilibration is a natural consequence of reasonable...

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Autor principal: Zwanzig, Robert
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19262/
https://ncbi.nlm.nih.gov/pubmed/8990176
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