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The Roles of Tyr391 and Tyr619 in RB69 DNA Polymerase Replication Fidelity
In the family-B DNA polymerase of bacteriophage RB69, the conserved aromatic palm-subdomain residues Tyr391 and Tyr619 interact with the last primer-template base pair. Tyr619 interacts via a water-mediated hydrogen bond with the phosphate of the terminal primer nucleotide. The main-chain amide of T...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1925234/ https://ncbi.nlm.nih.gov/pubmed/17321543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.01.067 |
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