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Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development

Several vertebrate microRNAs (miRNAs) have been implicated in cellular processes such as muscle differentiation, synapse function, and insulin secretion. In addition, analysis of Dicer null mutants has shown that miRNAs play a role in tissue morphogenesis. Nonetheless, only a few loss-of-function ph...

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Détails bibliographiques
Auteurs principaux: Kloosterman, Wigard P, Lagendijk, Anne K, Ketting, René F, Moulton, Jon D, Plasterk, Ronald H. A
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925136/
https://ncbi.nlm.nih.gov/pubmed/17676975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050203
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