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Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development

Several vertebrate microRNAs (miRNAs) have been implicated in cellular processes such as muscle differentiation, synapse function, and insulin secretion. In addition, analysis of Dicer null mutants has shown that miRNAs play a role in tissue morphogenesis. Nonetheless, only a few loss-of-function ph...

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Autors principals: Kloosterman, Wigard P, Lagendijk, Anne K, Ketting, René F, Moulton, Jon D, Plasterk, Ronald H. A
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925136/
https://ncbi.nlm.nih.gov/pubmed/17676975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050203
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