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Multiplex SNaPshot for detection of BRCA1/2 common mutations in Spanish and Spanish related breast/ovarian cancer families

BACKGROUND: It is estimated that 5–10% of all breast cancer are hereditary and attributable to mutations in the highly penetrance susceptibility genes BRCA1 and BRCA2. The genetic analysis of these genes is complex and expensive essentially because their length. Nevertheless, the presence of recurre...

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Bibliographische Detailangaben
Hauptverfasser: Filippini, Sandra, Blanco, Ana, Fernández-Marmiesse, Ana, Álvarez-Iglesias, Vanesa, Ruíz-Ponte, Clara, Carracedo, Ángel, Vega, Ana
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924843/
https://ncbi.nlm.nih.gov/pubmed/17603881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-8-40
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