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Multiplex SNaPshot for detection of BRCA1/2 common mutations in Spanish and Spanish related breast/ovarian cancer families

BACKGROUND: It is estimated that 5–10% of all breast cancer are hereditary and attributable to mutations in the highly penetrance susceptibility genes BRCA1 and BRCA2. The genetic analysis of these genes is complex and expensive essentially because their length. Nevertheless, the presence of recurre...

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Detalhes bibliográficos
Main Authors: Filippini, Sandra, Blanco, Ana, Fernández-Marmiesse, Ana, Álvarez-Iglesias, Vanesa, Ruíz-Ponte, Clara, Carracedo, Ángel, Vega, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924843/
https://ncbi.nlm.nih.gov/pubmed/17603881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-8-40
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