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Anchoring of Protein Kinase A-Regulatory Subunit IIα to Subapically Positioned Centrosomes Mediates Apical Bile Canalicular Lumen Development in Response to Oncostatin M but Not cAMP

Oncostatin M and cAMP signaling stimulate apical surface-directed membrane trafficking and apical lumen development in hepatocytes, both in a protein kinase A (PKA)-dependent manner. Here, we show that oncostatin M, but not cAMP, promotes the A-kinase anchoring protein (AKAP)-dependent anchoring of...

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Bibliografiske detaljer
Main Authors: Wojtal, Kacper A., Hoekstra, Dick, van IJzendoorn, Sven C.D.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924835/
https://ncbi.nlm.nih.gov/pubmed/17494870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0732
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