Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of β cells

The pathogenesis of type 1 diabetes (T1D) involves the immune-mediated destruction of insulin-producing β cells in the pancreatic islets of Langerhans. Genetic analysis of families with a high incidence of T1D and nonobese diabetic (NOD) mice, a prototypical model of the disorder, uncovered multiple...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Enzler, Thomas, Gillessen, Silke, Dougan, Michael, Allison, James P., Neuberg, Donna, Oble, Darryl A., Mihm, Martin, Dranoff, Glenn
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2007
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924767/
https://ncbi.nlm.nih.gov/pubmed/17483299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-08-043786
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky