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Peripheral deletion of mature alloreactive B cells induced by costimulation blockade

Alloreactive B cells can contribute to graft rejection. Anti-CD154 treatment together with donor-specific transfusion (DST) results in the long-term survival of MHC-mismatched mouse heart grafts and inhibition of alloantibody production. To characterize the mechanism of B cell tolerance induced by t...

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Main Authors: Li, Yijin, Ma, Lianli, Shen, Jikun, Chong, Anita S.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924566/
https://ncbi.nlm.nih.gov/pubmed/17609366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705240104
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