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Peripheral deletion of rheumatoid factor B cells after abortive activation by IgG

Rheumatoid factor (RF) B cells proliferate during secondary immune responses to immune complexed antigen and antigen specific T cells, but higher affinity RFs are not detected except in patients with rheumatoid arthritis and other autoimmune diseases. Consequently, there must exist highly efficient...

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Библиографические подробности
Главные авторы: Tighe, Helen, Warnatz, Klaus, Brinson, Diana, Corr, Maripat, Weigle, William O., Baird, Stephen M., Carson, Dennis A.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences of the USA 1997
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC19567/
https://ncbi.nlm.nih.gov/pubmed/9012838
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