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ΔNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2

p63, a homologue of the tumor suppressor p53, is pivotal for epithelial development, because its loss causes severe epithelial dysgenesis, although no information is so far available on the role of p63 in the thymus. We identified the expression of all p63 isoforms in the developing thymus. The p63(...

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Autores principales: Candi, Eleonora, Rufini, Alessandro, Terrinoni, Alessandro, Giamboi-Miraglia, Alessandro, Lena, Anna Maria, Mantovani, Roberto, Knight, Richard, Melino, Gerry
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924561/
https://ncbi.nlm.nih.gov/pubmed/17626181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703458104
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