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Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase

The mitogen-activated protein kinases ERK (extracellular signal-regulated kinase), JNK (c-Jun N-terminal kinase), and p38 phosphorylate and activate transcription factors that promote proliferative and inflammatory responses, whereas glucocorticoid receptor (GR) activation inhibits cell growth and i...

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Bibliographic Details
Main Authors: Rogatsky, Inez, Logan, Susan K., Garabedian, Michael J.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC19245/
https://ncbi.nlm.nih.gov/pubmed/9482836
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