In vitro activities of penciclovir and acyclovir against herpes simplex virus types 1 and 2.

Penciclovir (PCV) and acyclovir are acyclic guanine analogs which inhibit herpes simplex virus (HSV) DNA polymerase. Their 50% infective doses were 0.5 to 0.8 microgram/ml for clinical isolates of HSV-1 and 1.3 to 2.2 micrograms/ml for HSV-2. Furthermore, HSV-infected cultures receiving 2-h pulses o...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Weinberg, A, Bate, B J, Masters, H B, Schneider, S A, Clark, J C, Wren, C G, Allaman, J A, Levin, M J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1329640/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.9.2037
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