Development of halofantrine resistance and determination of cross-resistance patterns in Plasmodium falciparum.
Intermittent exposure to halofantrine (HF) of both chloroquine-susceptible (T9.96) and chloroquine-resistant (K1) isolates of Plasmodium falciparum in vitro resulted in a rapid reduction in susceptibility to HF. After 6 months, the 50% inhibitory concentration (IC50) of HF, determined with [G-3H]hyp...
保存先:
| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1993
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192389/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8285616/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.11.2337 |
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