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An early, abundant cytotoxic T-lymphocyte response against Theiler's virus is critical for preventing viral persistence.

In genetically susceptible strains of mice, the DA strain of Theiler's virus, a picornavirus, causes a persistent infection of the white matter of the spinal cord associated with chronic demyelination. In resistant strains, on the other hand, the infection is cleared within 1 to 2 weeks. In this art...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Dethlefs, S, Brahic, M, Larsson-Sciard, E L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192357/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343251/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8875-8878.1997
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