An early, abundant cytotoxic T-lymphocyte response against Theiler's virus is critical for preventing viral persistence.
In genetically susceptible strains of mice, the DA strain of Theiler's virus, a picornavirus, causes a persistent infection of the white matter of the spinal cord associated with chronic demyelination. In resistant strains, on the other hand, the infection is cleared within 1 to 2 weeks. In this art...
Guardado en:
| Publicado en: | J Virol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1997
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343251/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8875-8878.1997 |
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