Structure-based identification of an inducer of the low-pH conformational change in the influenza virus hemagglutinin: irreversible inhibition of infectivity.
Past efforts to employ a structure-based approach to design an inhibitor of the fusion-inducing conformational change in the influenza virus hemagglutinin (HA) yielded a family of small benzoquinones and hydroquinones. The most potent of these, tert-butyl hydroquinone (TBHQ), inhibits both the confo...
Сохранить в:
| Опубликовано в:: | J Virol |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
1997
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192347/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8808-8820.1997 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
|