Structure-based identification of an inducer of the low-pH conformational change in the influenza virus hemagglutinin: irreversible inhibition of infectivity.
Past efforts to employ a structure-based approach to design an inhibitor of the fusion-inducing conformational change in the influenza virus hemagglutinin (HA) yielded a family of small benzoquinones and hydroquinones. The most potent of these, tert-butyl hydroquinone (TBHQ), inhibits both the confo...
Na minha lista:
| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1997
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192347/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8808-8820.1997 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|