RNA aptamers specifically interact with the prion protein PrP.

We have isolated RNA aptamers which are directed against the recombinant Syrian golden hamster prion protein rPrP23-231 (rPrPc) fused to glutathione S-transferase (GST). The aptamers did not recognize the fusion partner GST or the fusion protein GST::rPrP90-231 (rPrP27-30), which lacks 67 amino acid...

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Autors principals: Weiss, S, Proske, D, Neumann, M, Groschup, M H, Kretzschmar, H A, Famulok, M, Winnacker, E L
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC192345/
https://ncbi.nlm.nih.gov/pubmed/9343239
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