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The adenovirus E3-10.4K/14.5K complex mediates loss of cell surface Fas (CD95) and resistance to Fas-induced apoptosis.

Cytotoxic T cells use Fas (CD95), a member of the tumor necrosis factor (TNF) receptor superfamily, to eliminate virus-infected cells by activation of the apoptotic pathway for cell death. The adenovirus E3 region encodes several proteins that modify immune defenses, including TNF-dependent cell dea...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Shisler, J, Yang, C, Walter, B, Ware, C F, Gooding, L R
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1997
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192288/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8299-8306.1997
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