The adenovirus E3-10.4K/14.5K complex mediates loss of cell surface Fas (CD95) and resistance to Fas-induced apoptosis.

Cytotoxic T cells use Fas (CD95), a member of the tumor necrosis factor (TNF) receptor superfamily, to eliminate virus-infected cells by activation of the apoptotic pathway for cell death. The adenovirus E3 region encodes several proteins that modify immune defenses, including TNF-dependent cell dea...

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Dettagli Bibliografici

Pubblicato in:	J Virol
Autori principali:	Shisler, J, Yang, C, Walter, B, Ware, C F, Gooding, L R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192288/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343182/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8299-8306.1997
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