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Mechanistic study of inhibition of levofloxacin absorption by aluminum hydroxide.

The mechanisms of reduction in absorption of levofloxacin (LVFX) by coadministration of aluminum hydroxide were studied. The partition coefficient of LVFX (0.1 mM) between chloroform and phosphate buffer (pH 5.0) was reduced by 60 to 70% with the addition of metal ions such as Cu2+, Al3+, and Fe2+ (...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Tanaka, M, Kurata, T, Fujisawa, C, Ohshima, Y, Aoki, H, Okazaki, O, Hakusui, H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1993
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC192246/
https://ncbi.nlm.nih.gov/pubmed/8257141
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