Treatment of murine cytomegalovirus infections in severe combined immunodeficient mice with ganciclovir, (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine, interferon, and bropirimine.

Severe combined immunodeficient (SCID) mice were found to be highly susceptible to murine cytomegalovirus (MCMV) infection. Treatment of infected mice with ganciclovir (12.5, 25, and 50 mg/kg of body weight for 10 days) starting 24 h after virus challenge resulted in delays in death by 2 to 8 days,...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Smee, D F, Morris, J L, Leonhardt, J A, Mead, J R, Holy, A, Sidwell, R W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1329629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.9.1837
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