Prediction of human pharmacokinetics of panipenem-betamipron, a new carbapenem, from animal data.
The pharmacokinetic behavior of panipenem (PAPM)-betamipron (BP), a new carbapenem, in humans was successfully predicted from data collected from six animal species. PAPM and BP were biphasically eliminated from plasma after intravenous (i.v.) administration of PAPM-BP to mice, guinea pigs, rats, ra...
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192191/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1416872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.9.1810 |
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