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Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity.

The herpes simplex virus DNA polymerase catalytic subunit, which has intrinsic polymerase and 3'-5' exonuclease activities, contains sequence motifs that are homologous to those important for 3'-5' exonuclease activity in other polymerases. The role of one such motif, Exo III, was examined in this s...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Hwang, Y T, Liu, B Y, Coen, D M, Hwang, C B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192131/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9311864/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.10.7791-7798.1997
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