Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity.

The herpes simplex virus DNA polymerase catalytic subunit, which has intrinsic polymerase and 3'-5' exonuclease activities, contains sequence motifs that are homologous to those important for 3'-5' exonuclease activity in other polymerases. The role of one such motif, Exo III, was examined in this s...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Hwang, Y T, Liu, B Y, Coen, D M, Hwang, C B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192131/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9311864/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.10.7791-7798.1997
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