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Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/P(i) cotransporter

We have studied the involvement of proteolytic pathways in the regulation of the Na/P(i) cotransporter type II by parathyroid hormone (PTH) in opossum kidney cells. Inhibition of lysosomal degradation (by leupeptin, ammonium chloride, methylamine, chloroquine, l-methionine methyl ester) prevented th...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Pfister, Markus F., Ruf, Isabelle, Stange, Gerti, Ziegler, Urs, Lederer, Eleanor, Biber, Jürg, Murer, Heini
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19212/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9465116/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.4.1909
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