Decreased cyclin B1 expression contributes to G2 delay in human brain tumor cells after treatment with camptothecin.

DNA damage produces delayed mitosis (G2/M delay) in proliferating cells, and shortening the delay sensitizes human malignant glioma and medulloblastoma cells to cytotoxic chemotherapy. Although activation of the cyclin-dependent kinase CDC2 mediates G2/M transition in all tumor cells studied to date...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Janss, A. J., Maity, A., Tang, C. B., Muschel, R. J., McKenna, W. G., Sutton, L., Phillips, P. C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2001
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920603/
https://ncbi.nlm.nih.gov/pubmed/11305412
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller