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Activation of SAPK/JNK by camptothecin sensitizes androgen-independent prostate cancer cells to Fas-induced apoptosis

We have previously shown that the androgen-independent prostate cancer cells DU145, despite expressing Fas and FasL, were resistant to anti-Fas-induced apoptosis, and that this resistance could be overcome by pretreating the cells with sublethal doses of camptothecin. Here, we provide evidence that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Costa-Pereira, A P, McKenna, S L, Cotter, T G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363235/
https://ncbi.nlm.nih.gov/pubmed/10839298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1149
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