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Heterologous Amyloid Seeding: Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease

Neurodegenerative diseases associated with abnormal protein folding and ordered aggregation require an initial trigger which may be infectious, inherited, post-inflammatory or idiopathic. Proteolytic cleavage to generate vulnerable precursors, such as amyloid-β peptide (Aβ) production via β and γ se...

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Библиографические подробности
Главные авторы: Jean, Létitia, Thomas, Benjamin, Tahiri-Alaoui, Abdessamad, Shaw, Michael, Vaux, David J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920558/
https://ncbi.nlm.nih.gov/pubmed/17653279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000652
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