Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity

DHEA, together with DHEAS, is the most abundant steroid in the blood of young adult humans. Levels in humans decline with age and during certain types of illness or stress. We have found that DHEA(S) can prevent or reduce the neurotoxic actions in the hippocampus of the glutamate agonists N-methyl-d...

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Главные авторы: Kimonides, V. G., Khatibi, N. H., Svendsen, C. N., Sofroniew, M. V., Herbert, J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1998
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC19202/
https://ncbi.nlm.nih.gov/pubmed/9465106
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