Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity

DHEA, together with DHEAS, is the most abundant steroid in the blood of young adult humans. Levels in humans decline with age and during certain types of illness or stress. We have found that DHEA(S) can prevent or reduce the neurotoxic actions in the hippocampus of the glutamate agonists N-methyl-d...

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Hauptverfasser: Kimonides, V. G., Khatibi, N. H., Svendsen, C. N., Sofroniew, M. V., Herbert, J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1998
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19202/
https://ncbi.nlm.nih.gov/pubmed/9465106
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