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Chemokine receptor CCR5 genotype influences the kinetics of human immunodeficiency virus type 1 infection in human PBL-SCID mice.

Individuals homozygous for a 32-bp deletion (delta 32) in the CCR5 gene encoding the coreceptor for macrophage-tropic human immunodeficiency virus type 1 (HIV-1) are resistant to virus infection, and heterozygous individuals show some slowing of disease progression. The impact of the CCR5 genotype o...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Picchio, G R, Gulizia, R J, Mosier, D E
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1997
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192012/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9261448/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.9.7124-7127.1997
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