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Mapping of independent V3 envelope determinants of human immunodeficiency virus type 1 macrophage tropism and syncytium formation in lymphocytes.

The V3 region of the human immunodeficiency virus type 1 (HIV-1) envelope protein is known to have a major influence on macrophage tropism as well as the ability to cause syncytium formation or fusion in CD4-positive lymphocyte cultures. Using infectious molecular HIV-1 clones, a series of mutant cl...

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Bibliographic Details
Main Authors: Chesebro, B, Wehrly, K, Nishio, J, Perryman, S
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC191011/
https://ncbi.nlm.nih.gov/pubmed/8971043
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