Active-site residues of cyclophilin A are crucial for its incorporation into human immunodeficiency virus type 1 virions.

Human immunodeficiency virus type 1 (HIV-1) incorporates the cellular peptidyl-prolyl cis-trans isomerase cyclophilin A (CyPA), the cytosolic receptor for the immunosuppressant cyclosporin A (CsA). CsA inhibits the incorporation of CyPA and reduces HIV-1 virion infectivity but is inactive against cl...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Dorfman, T, Weimann, A, Borsetti, A, Walsh, C T, Göttlinger, H G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9261445/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.9.7110-7113.1997
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