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Enhanced downregulation of Lck-mediated signal transduction by a Y114 mutation of herpesvirus Saimiri tip.

Tip of herpesvirus saimiri associates with Lck and downregulates Lck function in cellular signal transduction. In this report, we demonstrate that mutation of tyrosine 114 of Tip significantly increases Lck-binding activity. This mutant exhibits a dramatic increase in the suppression of cellular tyr...

詳細記述

保存先:
書誌詳細
主要な著者: Guo, J, Duboise, M, Lee, H, Li, M, Choi, J K, Rosenzweig, M, Jung, J U
フォーマット: Artigo
言語:Inglês
出版事項: 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC192003/
https://ncbi.nlm.nih.gov/pubmed/9261442
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