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Functional and structural analysis of the sialic acid-binding domain of rotaviruses.

The infectivity of most animal rotaviruses is dependent on the interaction of the virus spike protein VP4 with a sialic acid (SA)-containing cell receptor, and the SA-binding domain of this protein has been mapped between amino acids 93 and 208 of its trypsin cleavage fragment VP8. To identify which...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Isa, P, López, S, Segovia, L, Arias, C F
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1997
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9261399/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.9.6749-6756.1997
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