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A 96-well DNase I footprinting screen for drug–DNA interactions

The established protocol for DNase I footprinting has been modified to allow multiple parallel reactions to be rapidly performed in 96-well microtitre plates. By scrutinizing every aspect of the traditional method and making appropriate modifications it has been possible to considerably reduce the t...

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Detalhes bibliográficos
Main Authors: Ellis, Tom, Evans, David A., Martin, Christopher R. H., Hartley, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1919508/
https://ncbi.nlm.nih.gov/pubmed/17586817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm467
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