Rad51 and Rad54 ATPase activities are both required to modulate Rad51-dsDNA filament dynamics

Rad51 and Rad54 are key proteins that collaborate during homologous recombination. Rad51 forms a presynaptic filament with ATP and ssDNA active in homology search and DNA strand exchange, but the precise role of its ATPase activity is poorly understood. Rad54 is an ATP-dependent dsDNA motor protein...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Xuan, Zhang, Xiao-Ping, Solinger, Jachen A., Kiianitsa, Konstantin, Yu, Xiong, Egelman, Edward H., Heyer, Wolf-Dietrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2007
Schlagworte:
Nucleic Acid Enzymes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1919488/
https://ncbi.nlm.nih.gov/pubmed/17567608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm412
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