Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1.

The chemokine receptor CCR5 is the major fusion coreceptor for macrophage-tropic strains of human immunodeficiency virus type 1 (HIV-1). To define the structures of CCR5 that can support envelope (Env)-mediated membrane fusion, we analyzed the activity of homologs, chimeras, and mutants of human CCR...

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Autores principales: Doranz, B J, Lu, Z H, Rucker, J, Zhang, T Y, Sharron, M, Cen, Y H, Wang, Z X, Guo, H H, Du, J G, Accavitti, M A, Doms, R W, Peiper, S C
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC191903/
https://ncbi.nlm.nih.gov/pubmed/9261347
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